You don't kill individual people. Each guy is like a capo with his own crew of hitmen, thugs and bodyguards. You kill them. You also take money, guns cars and stuff. No you can't kill the boss and takeover. If you don't like a guy join a family that is enemy to that fam. There are 3 strategies. 1. Collect, build up your forces, defend your city and alliance but only attack those who attack first. Send all excess cash to bankers who can't be attacked. 2. Looters, run around from city to city attacking anyone weaker and taking their stuff. 3. Collecters-attackers, families that build up their strength to attack and zero out someone they don't like or a city they want to control. No you don't attack members of your own family tessio.